Affordable overdose-reversal medicine now available to any Californian

Kristen Hwang · April 25, 2025

Affordable overdose-reversal medicine now available to any Californian

Any Californian can purchase naloxone, an opioid overdose reversal medication, directly from the state at a discounted price, Gov. Gavin Newsom’s office announced Monday.

The medication is available online for $24 for a two-pack of the nasal spray, roughly half the market price of the drug. Previously, the discount was available only to government organizations and businesses.

“Life-saving medications shouldn’t come with a life-altering price tag. CalRx is about making essential drugs like naloxone affordable and accessible for all — not the privileged few,” Newsom said in a statement. CalRx is a Newsom initiative to bring down the cost of prescription drugs.

California has spent more than $1 billion fighting the opioid epidemic, which killed more than 8,900 people last year, according to preliminary data from the state health department.

That represents a 13% increase in deaths from 2023.

The Naloxone Distribution Project and Access Initiative is part of the strategy to stop overdoses, which began spiking in 2019 as fentanyl, a highly potent synthetic opioid, infused the market. The rate of fentanyl-related overdose deaths began declining last year, according to state data.

More than 6 million naloxone kits have been distributed to local governments and organizations since 2018,…

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